Genome-wide identification and characterization of transcripts translationally regulated by bacterial lipopolysaccharide in macrophage-like J774.1 cells Running title: Effect of LPS on translation in macrophages
نویسندگان
چکیده
From Laboratory for Immunogenomics and Laboratory for Immunological Memory, RIKEN Research Center for Allergy and Immunology, Yokohama; and Laboratory of Genome Technology, Department of Human Gene Research, Kazusa DNA Research Institute, Chiba, Japan *Correspondence to: Hiroshi Kitamura, D.V.M., Ph.D. Laboratory for Immunogenomics RIKEN Research Center for Allergy and Immunology 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan E-mail: [email protected], Tel: +81-45-503-9696, Fax: +81-45-503-9694 Page 1 of 58 Articles in PresS. Physiol Genomics (January 29, 2008). doi:10.1152/physiolgenomics.00095.2007
منابع مشابه
Genome-wide identification and characterization of transcripts translationally regulated by bacterial lipopolysaccharide in macrophage-like J774.1 cells.
Although Escherichia coli LPS is known to elicit various proinflammatory responses in macrophages, its effect on the translational states of transcripts has not yet been explored on a genome-wide scale. To address this, we investigated the mRNA profiles in polysomal and free messenger ribonucleoprotein particle (mRNP) fractions of mouse macrophage-like J774.1 cells, using Affymetrix Mouse Genom...
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